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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RUNX3 All Species: 3.03
Human Site: T231 Identified Species: 6.06
UniProt: Q13761 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13761 NP_001026850.1 415 44356 T231 H F S S Q P Q T P I Q G T S E
Chimpanzee Pan troglodytes XP_001168112 361 38974 P178 F S S Q P Q T P I Q G T S E L
Rhesus Macaque Macaca mulatta XP_001113682 501 52667 H317 D V E T N P L H S H S E N Q K
Dog Lupus familis XP_544492 414 44288 D231 E A V S A A T D C A P C R P P
Cat Felis silvestris
Mouse Mus musculus Q64131 409 43610 Q226 T T S H F S S Q P K T P I Q G
Rat Rattus norvegicus Q63046 450 48538 M240 N P Q P Q S Q M Q D A R Q I Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232978 334 36473 F151 S I S T P S H F G S Q A Q T P
Frog Xenopus laevis Q6PF39 462 50351 S278 V H P A T P I S P G R A S S M
Zebra Danio Brachydanio rerio NP_571679 424 45996 D235 G L W P D Q I D P P T L K T C
Tiger Blowfish Takifugu rubipres NP_001092121 407 44638 A223 A H L S T T Q A L W Q E Q M D
Fruit Fly Dros. melanogaster Q9W349 826 84703 V483 P T G G G G G V A A G G V A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q9ATN1 302 31144 T119 C A G L A V A T V I L S T G H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 63 48.6 N.A. 91.5 59.5 N.A. N.A. 68.9 56.9 68.1 67.9 23.3 N.A. N.A. N.A.
Protein Similarity: 100 86.9 68.2 56.1 N.A. 94.6 70.4 N.A. N.A. 74.2 69 75.2 77.3 33.1 N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 6.6 N.A. 13.3 13.3 N.A. N.A. 13.3 20 6.6 20 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 20 6.6 N.A. 13.3 26.6 N.A. N.A. 26.6 46.6 13.3 26.6 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 20 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 30.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 20 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 0 9 17 9 9 9 9 17 9 17 0 9 0 % A
% Cys: 9 0 0 0 0 0 0 0 9 0 0 9 0 0 9 % C
% Asp: 9 0 0 0 9 0 0 17 0 9 0 0 0 0 9 % D
% Glu: 9 0 9 0 0 0 0 0 0 0 0 17 0 9 9 % E
% Phe: 9 9 0 0 9 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 9 0 17 9 9 9 9 0 9 9 17 17 0 9 17 % G
% His: 9 17 0 9 0 0 9 9 0 9 0 0 0 0 9 % H
% Ile: 0 9 0 0 0 0 17 0 9 17 0 0 9 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 9 % K
% Leu: 0 9 9 9 0 0 9 0 9 0 9 9 0 0 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 9 % M
% Asn: 9 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 9 9 9 17 17 25 0 9 34 9 9 9 0 9 17 % P
% Gln: 0 0 9 9 17 17 25 9 9 9 25 0 25 17 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 9 9 9 0 0 % R
% Ser: 9 9 34 25 0 25 9 9 9 9 9 9 17 17 0 % S
% Thr: 9 17 0 17 17 9 17 17 0 0 17 9 17 17 0 % T
% Val: 9 9 9 0 0 9 0 9 9 0 0 0 9 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _